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Purpose To evaluate IVIM in the assessment of renal dysfunction compared with a mono-exponential model.Methods Fifty-four subjects were enrolled into this study.The estimated glomerular filtration rate(eGFR)was assessed to classify the subjects as having severe renal injury group(sRI,eGFR < 30 ml/min/1.73 m2)or not(non-sRI).A free-breathing DWI with 7 bfactors was performed.