Introduction: The intestinal epithelial barrier plays a critical role in host defense against luminal pathogens.Ethanol (EtOH) and dietary components may alter barrier integrity resulting in increased
Psoriasis is a multifactorial skin disease and it brings a lot of inconvenient in patients life.Thus, it is urgent to develop efficient and low toxicity drugs that can cure psoriasis.
Cre-recombinase (CRB) over-expressed mouse driven by a different promoter is normally used for conditional gene inactivation in various tissues.The specificity of this conditional knockout tool is dep
Pikahei-1(t) is the strongest quantitative trait locus (QTL) for blast resistance in upland rice cv.Kahei, which has strong field resistance to the rice blast disease.
Pancreatic islets are the main organ to maintain glucose homeostasis by beta cells of which secreting insulin and alpha cells of which secreting glucagon.
Elevated circulating free fatty acid (FFA) levels are major contributors to insulin resistance in the muscle and liver, but the underlying mechanisms require further elucidation.
Geranylgeranyl diphosphate synthase (GGPPS) is a branching enzyme in mevalonate pathway that synthesizes geranylgeranyl diphosphate (GGPP) from its substrate farnesyl diphosphate (FPP).
In the mammalian ovary, primordial follicles activate from the dormant pool and develop until either ovulation occurs or follicles undergo atresia.
Dysregulation of ribosome biogenesis causes human diseases, such as Diamond-Blackfan anemia, 5q minus syndrome and bone marrow failure.
中华鳖是重要的名特优水产养殖动物,由于缺少商品化的细胞系,其病毒性疾病的防治研究难以深入开展；本研究旨在建立连续的中华鳖心肌成纤维细胞系。以中华鳖心肌组织为材料,采用半消化法对心肌组织进行消化,将心肌组织剪成1 mm3的组织块,之后转入25cm2细胞培养瓶,使之均匀铺满瓶底,添加2ml培养液倒置培养,3d之后补充培养液至10ml并翻转培养瓶正置培养。采用RPMI1640, MEM,DMEM 3种培