论文部分内容阅读
Background Neurosyphilis (NS) is difficult to diagnose especially in syphilis patients with negative cerebrospinal fluid (CSF) Rapid Plasma Reagin (RPR) or Venereal Disease Research Laboratory (VDRL).Methods We conducted a cross-sectional study and analysis of macrophage migration inhibitory factor (MIF) in syphilitic patients to identify a novel marker for the diagnosis of NS,with a focus on probable NS (NS with negative VDRL/RPR).