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Incidence of autoimmune disease is increasingMultiple Sclerosis,Diabetes,Lupus Incidence (per 100,000) of diabetes in children under 10 in Norway(～4-fold increase over 50 years) How should a positive autoantibody finding in an asymptomatic subject be interpreted?1.Are the Abs predictive of a disease?2.Are the Abs an epiphenomenon?3.Are the results false positives ?