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5. Cooperative Actions of Protein Kinases to Orchestrate Chromosome Segregation in Mitosis

Cooperative Actions of Protein Kinases to Orchestrate Chromosome Segregation in Mitosis

来源 :中国细胞生物学学会2015年全国学术大会 | 被引量 : 0次 | 上传用户：hstiantian

【摘 要】

：

Histone modifications coordinate the chromatin localization of key regulatory factors in mitosis[1].For example, mitotic phosphorylation of Histone H3 threonine-3 (H3T3ph) by Haspin is required for ce

【作 者】

：

Linli Zhou Xiaoying Tian Jonathan Higgins Fangwei Wang 

【机 构】

：

Zhejiang University, Life Sciences Institute, Hangzhou, China, 310058

【出 处】

：

中国细胞生物学学会2015年全国学术大会

【发表日期】

：

2015年4期

【关键词】

：

Mitosis Histone phosphorylation Centromere Protein kinase Haspin 

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　　Histone modifications coordinate the chromatin localization of key regulatory factors in mitosis[1].For example, mitotic phosphorylation of Histone H3 threonine-3 (H3T3ph) by Haspin is required for centromeric localization of Aurora B[2,3], a key player in the regulation of kinetochore-microtubule attachments.

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