Terahertz(THz)wave refers to the frequency ranging from 0.1 to 10 THz.THz radiation excites low-frequency molecular vibrations from intra/inter-molecular domains connected by the weak interactions including hydrogen bonds,van der Waals and non-bonded(hydrophobic)interactions etc.The energy level of THz wave largely coincides with the level of the biomolecular low-frequency motions such as vibration,rotation and translation of the molecular skeleton.