Ethnopharmacological relevance: Potentilla fruticosa,also called "Jinlaomei" and "Gesanghua",is widely used as folk herbs in traditional Tibetan medicine in China to treat inflammations,wounds,certain forms of cancer,diarrhoea,diabetes and other ailments.Aim of the study: Previous research found P.fruticosa leaf extracts (C-3) combined with Ginkgo biloba extracts (EGb) showed obvious synergistic effects in a variety of oxidation systems.The aim of the present study was to further confirm the synergy of P.fruticosa combined with EGb viewed from physiological bioavailability and explore the related bioactive mechanism behind the synergism.