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Purpose:To differentiate papillary RCC (pRCC) from chromophobe RCC (CRCC) based on intratumoral susceptibility signals (ITSSs) detected on SWI. Materials and Methods:A retrospective review was performed of patients with pRCC (n=12) or CRCC (n=9) who were proven by pathology. The ITSSs were classified into hemorrhage and mircovessels based on their morphology. Nonparametric Mann-Whitney test was used to compare the differences in the dominant structure of ITSSs, the number of intratumoral hemorrhagic lesions and vessels, and the ratio of ITSS area on SWI between pRCC and CRCC. The diagnostic values of the dominant structure of ITSSs, the number of intratumoral hemorrhagic lesions and vessels, and the ratio of ITSS area on SWI in differentiating pRCCs from CRCCs were compared by receiver operating characteristics (ROC).