健康产品检验研究中替代方法的研究进展

来源 :2015毒性测试替代方法与转化毒理学(国际)学术研讨会 | 被引量 : 0次 | 上传用户:nufjin
下载到本地 , 更方便阅读
声明 : 本文档内容版权归属内容提供方 , 如果您对本文有版权争议 , 可与客服联系进行内容授权或下架
论文部分内容阅读
近几年来,国际上动物实验替代方法的研究与验证工作发展很快,特别是在药品和化妆品等安全性评价领域,许多替代方法已通过验证或正在验证之中.替代方法的应用不仅可以减少实验动物的使用量,降低检验成本,缩短检验时间,更重要的是利用替代方法可以从不同层面开展毒理机制研究,保证检验结果的准确性,提高检验的科学性.同时,替代方法的研究与应用,也是打破国际贸易中一些国家和地区设置的技术壁垒的基础保障.
其他文献
  Increasingly, there is a move toward using in vitro toxicity testing for assessment of human health risk of chemicals.As with in vivo toxicity testing, an i
会议
  Estrogen receptor belongs to Type Ⅰ nuclear receptors which are largely located in the cytosol of cells in complex with heat shock proteins in the absence
会议
  The use of in vitro safety test methods by the cosmetics, personal care, and household products industries in North America and Europe has progressively rep
会议
  Approaches to toxicological hazard and risk assessment are advancing at an unprecedented rate, particularly in relation to the "3R" objective of replacement
会议
  Unilever has a long history of assessing and managing the risk to the environment from the chemicals in our products.This talk will reflect on the scientifi
会议
  There are ethical, business, scientific and legislative drivers to replace, refine,and reduce the use of animals in research and testing.Across many areas o
会议
  Toxicological testing in the current regulatory environment is steeped in a history of using animals to answer questions about the safety of products to whi
会议
  In the future, toxicity testing will rely on the power of modern molecular biology to identify perturbations in cellular function that are processed by a qu
会议