2. 您的位置
3. 首页
4. 会议论文
5. Protective effects of astaxanthin against oxygen and glucose deprivation damage via the PI3K/Akt/GSK

Protective effects of astaxanthin against oxygen and glucose deprivation damage via the PI3K/Akt/GSK

来源 :中国药理学会北美分会药理学学术大会 | 被引量 : 0次 | 上传用户：pilot111

【摘 要】

：

The study aimed to observe the protective effects of astaxanthin(ATX)and its molecular mechanism in SH-SY5Y cells.The SH-SY5Y cells were pre-treated with ATX(5,10,20 and 40 μmol/L)for 24 h and were co

【作 者】

：

Dong YAN Wen-guo JIANG Hai-bo ZHU Shu-cui LI Shu-ping ZHANG 

【机 构】

：

Department of Pharmacology,Binzhou Medical University,Yantai 264003,China

【出 处】

：

中国药理学会北美分会药理学学术大会

【发表日期】

：

2017年10期

【关键词】

：

astaxanthin SH-SY5Y OGD PI3K/Akt GSK3β Nrf2 

下载到本地 , 更方便阅读

下载此文 赞助VIP

声明 : 本文档内容版权归属内容提供方 , 如果您对本文有版权争议 , 可与客服联系进行内容授权或下架

论文部分内容阅读

　　The study aimed to observe the protective effects of astaxanthin(ATX)and its molecular mechanism in SH-SY5Y cells.The SH-SY5Y cells were pre-treated with ATX(5,10,20 and 40 μmol/L)for 24 h and were co-treated with OGD for 3 h.

其他文献

The role of L-type amino acid transporters in the uptake of glyphosate across mammalian epithelial t

Glyphosate is one of the most commonly used herbicides worldwide and reported low toxicity to humans.

会议

Impacts of lipophilic segment of amphiphilic block copolymers on the activity of P-glycoprotein in M

P-glycoprotein (P-gp) encoded by multidrug resistance 1 (MDR1) gene is an ATP-dependent drug efflux transporters and is expressed in mammalian and human tissues including liver, kidney, pancreas and i

会议

Simultaneous Quantification of IMM-H004 and Its Active Glucuronide Metabolite in Rat Plasma by LC-MS

IMM-H004 is a novel neuroprotective agent. The major metabolite of IMM-H004 in rats and human is the glucuronide conjugate (IMM-H004G).

会议

The vital role of BBB P-glycoprotein in brain exposure and fetal respiratory depression of narcotic

Narcotic analgesics (opiates or opioid analgesics) are a group of drugs that relieve acute and chronic severe pain by binding to opioid receptors.

会议

Mass spectrometry technology for detection and identification of unknown xenobiotics: next frontier

Due to the advantages of mass spectrometry technology, proteomics and metabolomics have made very significant progresses in the past 15 years.

会议

Impact of the co-administered Chinese herbs on the double anticoagulant therapy with clopidogrel and

With the introduction of Integrative Medicine in Hong Kong(“)s healthcare system, innovative models of interface are being developed to facilitate patients(“)choice on Chinese Medicine, Western Medici

会议

Interventional effect of prostaglandin E1 on the expression of Apaf-1 and TLR4 in the rats with cere

The present study aimed to observe the interventional effect of prostaglandin E1 on the expression of Apaf-1 and TLR4 in the rats with cerebral ischemia-reperfusion(CIR)injury.

会议

prostaglandin E1ratscerebral ischemia-reperfusionapoptotic protease activatin

Effects of chronic mild stress on behavioral and neurobiological parameters-role of glucocorticoid

Major depression is thought to originate from maladaptation to adverse events,particularly when impairments occur in mood-related brain regions.Hypothalamuspituitary-adrenal(HPA)axis is one of the maj

会议

depressionchronic mild stressGRFKBP5BDNFGap junction

Enhanced scratching elicited by a pruritogen and an algogen in a mouse model of contact hypersensiti

Chemical pruritogens and algogens evoke primarily itch and pain,respectively,when administered to the skin of healthy human subjects.However,the dominant sensory quality elicited by an algesic chemica

会议

contact hypersensitivityitchpainpruritogenalgogen

Rosuvastatin preconditioning inhibits inflammatory cytokines release in VSMCs of MCA after cerebral

The present study aimed to observe the effect of rosuvastatin preconditioning on inflammatory cytokines-IL-1β and IL-6 release in vascular smooth muscle cells(VSMCs)after ischemia reperfusion.Thirty-s

会议

rosuvastatininflammatory cytokinesIL-1βIL-6vascular smooth muscle cellsisch